- 1 How does Profhilo work?
- 2 What do fillers do?
- 3 Since Profhilo and fillers are both HAs, what’s the difference?
- 4 Profhilo versus Fillers: Comparison, Review, Price
- 5 Is Profhilo better than fillers?
- 6 How does Profhilo lift differently from fillers?
- 7 Should Profhilo be done before or after fillers? Or can it be done concurrently?
How does Profhilo work?Profhilo introduces a new category in the injectable market – bioremodelling. Using a patented (NAHYCO) technology that thermally stabilise Hyaluronic Acid without the use of chemical cross-linking agents, it is able to demonstrate the unique function of remodelling multi-layer skin tissue – from improving hydration status and texture of the skin to treating moderate skin laxity.
What do fillers do?Conventional HA dermal fillers contain HA that aims to volumise – for example in the use of augmenting a certain feature like a more prominent chin, a higher nose. The use of fillers in anti-aging is mainly to replace the volume that we lose in the mid-face as age. This provides an instant lift.
Since Profhilo and fillers are both HAs, what’s the difference?The reason why they have different properties is due to the way that they are cross-linked and the molecular weight of HA.
Profhilo is stabilised with a patented thermal technology without the use of chemical bonds. This allows
- Low viscosity – it allows the product to have a high concentration of HA and yet ‘watery’ enough to spread 2cm from the injection point under the skin.
- Increase availability of Porfhilo to bind to water to provide deep hydration effects
- On the other hand, HA fillers are usually BDDE crosslinked to increase viscosity and G’ – which is important so that the fillers are to stay and shape and resist impacts of external pressure
Molecular weightProfhilo contains patented hybrid HA complexes of a combination of high and low molecular weight. Low molecular weight complex is responsible for binding to water, providing the hydration effects. Whereas High molecular weight complexes provides a stable HA architecture in the dermis that allows volumetric replacement – giving the ‘Lift’ effect. The different molecular weights penetrate to the different depts of the skin – from the dermis to the superficial adipose layer to kickstart collagen and elastin bioremodelling process. This collagen building process results in a natural lifting effect. A dermal filler used to volumise an area usually contains high molecular weight HA cross-linked in BDDE. This will allow the filler to be higher in viscosity, more cohesive that will means that it will be structurally ‘harder’ to take the shape of the area where it ‘fills’. By structurally filling hollow areas where it fills
Profhilo versus Fillers: Comparison, Review, Price
|Ingredients||HA of different molecular weight 64mg/2mls per session||High molecular weight 20-24mg/ml per syringe|
|Cross-linking||Patented thermal NAHYCO technology||BDDE (Chemically) cross-linked|
|Bio-remodelling/ Collagen stimulation||+++||–|
|Indication||Skin laxity for moderate sagginess ~40 years||Replace volume (of the midface for rejuvenation)|
|Treatment area||Lower face, neck, décolletage. Possible area of upper face, body parts like knee, hands||Usually for the volume replacement of the cheeks and mid face for rejuvenation.|
|Treatment regime||2 sessions, 1 month apart||About once a year|
|Administration||BAP technique, 10 points||1 or 2 point injection per treatment area|
|Downtime||Minimal swelling that resolves in ~2 hours||Minimal to no downtime|
|Cost/ Price||$1000-$1500/ session||~ $800 per syringe|