Hydrated and rejuvenated skin is something many people aspire to; that’s why injectable treatments like Profhilo and Rejuran have gained significant popularity. Many aesthetic professionals recommend both treatments for their ability to improve skin quality, combat signs of ageing and cater to various skin concerns. But how do these two treatments differ?
This guide unpacks everything you need to know about Profhilo and Rejuran. From their unique formulations and costs to their benefits and results, we’ll help you decide which option best aligns with your goals.
What is Profhilo?
Profhilo is an injectable skin treatment designed specifically to improve skin hydration and elasticity while minimising the appearance of fine lines. Unlike dermal fillers, which primarily add volume, Profhilo is a bio-remodelling treatment. It consists of high concentrations of pure hyaluronic acid (HA), a naturally occurring substance in the human body known for its hydration properties. Upon injection, it spreads evenly under the skin, stimulating collagen and elastin production. This process promotes better skin texture, firmness and radiance.
Key Benefits of Profhilo
- Deep hydration. Profhilo’s hyaluronic acid helps restore and lock in moisture, leaving your skin plumper.
- Stimulates collagen and elastin production. It helps improve skin elasticity for a firmer, more youthful appearance.
- Versatile treatment areas. This product is suitable for the face, neck, hands, arms and décolletage.
- Minimal downtime. Treatment sessions are quick and involve mild, temporary side effects such as redness or swelling.
Profhilo is particularly effective for individuals experiencing signs of ageing, such as sagging skin and loss of elasticity.
What is Rejuran?
Rejuran, on the other hand, is a range of products which focuses on repairing and rejuvenating damaged skin. These include Rejuran Healer, Rejuran i, Rejuran s, and Rejuran HB Plus. These products utilise polynucleotides (PN) derived from salmon DNA, which are highly biocompatible with human skin. These molecules work at a cellular level to promote skin regeneration and healing.
Rejuran targets skin concerns like acne scars, fine lines and uneven skin tone. It is often called ‘skin healer’ or ‘salmon DNA therapy’ due to its restorative properties that stimulate collagen synthesis and reduce inflammation.
Key Benefits of Rejuran
- Repairs damaged skin. Rejuran encourages cellular repair to address scarring, fine lines and other imperfections.
- Promotes long-term healing. It helps enhance collagen production to maintain long-term skin renewal.
- Targets delicate areas. This injectable targets under-eye regions and acne-scarred skin.
- Skin texture improvements. It may help even out rough and dry skin.
Rejuran is ideal for those focusing on long-term skin repair and regeneration, making it a good option for individuals dealing with visible skin damage.
Profhilo vs Rejuran: Cost Comparison
For many people, the cost is often a critical factor when choosing between treatments. Here’s a breakdown of the price ranges for each product:
- Profhilo: Costs around $700–$1,200 per session
- Rejuran: Costs between $400–$1,000 per session
Factors Affecting Cost
- Treatment area. Larger treatment areas generally require a higher dosage, influencing the total cost.
- Number of sessions. Follow-up sessions are recommended in the following months if you want to maintain the effects of the product.
- Practitioner’s expertise and clinic location. Clinics with experienced aesthetic practitioners or those based in premium locations tend to charge more.
Both treatments typically require initial sessions followed by maintenance treatments every 6 to 12 months.
5 Key Differences Between Profhilo and Rejuran
While both skin rejuvenation treatments aim to improve skin quality and address ageing concerns, their ingredients, applications and effects differ significantly.
1. Ingredients and Mechanism
Profhilo is formulated with high concentrations of stabilised hyaluronic acid and is designed to provide intense hydration and support bio-remodelling. On the other hand, Rejuran leverages polynucleotides extracted from salmon DNA to promote skin repair at a cellular level.
| Feature | Profhilo | Rejuran |
|---|---|---|
| Main Ingredient | Hyaluronic Acid (HA) | Polynucleotides (PN) |
| Purpose | Hydration and lifting | Skin repair and regeneration |
2. Target Areas
Profhilo is designed to treat larger areas like the cheeks, neck, arms and hands, as it disperses easily beneath the skin. In contrast, Rejuran is better suited for smaller, targeted areas, such as under the eyes, making it ideal for delicate or damaged skin. It can also be used in the neck.
3. Results and Longevity
Profhilo provides visible improvements within 2 to 3 weeks, with results lasting up to 6 months. Rejuran, meanwhile, takes 2 to 4 weeks to show results, which typically last up to 12 months, depending on skin type and care.
4. Treatment Downtime
Profhilo offers minimal downtime, with most people experiencing only mild redness or swelling that typically subsides within a few hours. Rejuran may require a slightly longer recovery time, as common side effects such as redness, swelling, or bruising can last 3 to 5 days.
5. Suitability for Skin Concerns
Profhilo is ideal for delivering deep hydration and addressing sagging or ageing skin, while Rejuran works best for tackling acne scars, fine lines and rough skin needing repair.
Which Is Right for You: Profhilo or Rejuran?
Choosing between Profhilo and Rejuran depends on your skin concerns, goals and budget. Here’s how to determine which treatment may suit you.
Suitability Based on Skin Concerns
Profhilo is ideal for individuals seeking hydration and improvement in skin elasticity, making it perfect for tackling dryness, fine lines and loss of firmness.
Rejuran, on the other hand, focuses on healing and skin rejuvenation, particularly targeting acne scars, pigmentation and overall skin repair. Consulting with an aesthetic practitioner can help pinpoint which concerns to prioritise.
Age and Skin Type
Younger individuals in their 20s and 30s may find Profhilo more suited for preventing early signs of ageing and maintaining a radiant complexion.
Meanwhile, those with mature skin or specific damage, such as scarring, may benefit more substantially from Rejuran. Both treatments cater to various skin types, but your practitioner can tailor advice to your unique profile.
Personal Preferences
If you prefer a minimally invasive procedure, Profhilo might be the better option as it typically relies on fewer injection points while delivering widespread results.
Rejuran, although slightly more intensive, offers significant benefits for those prioritising long-term skin repair and regeneration.
Number of Injections
Profhilo generally requires as few as five injection points per session using the Bio Aesthetic Points (BAP) Technique, providing a quicker treatment process. The BAP Technique uses only 10 injections per session.
Rejuran, by contrast, involves more localised applications to target specific areas, which may require additional precision and time during the procedure.
Frequency of Treatment
Profhilo starts with two sessions spaced approximately one month apart. Meanwhile, Rejuran needs three to four treatment sessions, each with a four-week interval.
Maintenance treatments are usually recommended every six months to a year, depending on individual results and preferences.
Want to learn more about these products? Book a consultation and talk to Dr Justin Boey of Sozo Aesthetic Clinic to determine which product suits your skin condition.
Conclusion
Choosing between Profhilo and Rejuran ultimately depends on your individual needs. Profhilo is a hydration-focused treatment that delivers smoother, plumper skin. Rejuran offers deep restorative benefits, helping to heal and renew damaged skin over time.
Understanding the key differences and discussing your skincare goals with a professional can lead to better results and a more satisfying treatment experience.
