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Home / Topical medications / Hydroquinone Triluma: What Is It, Cost, How It Works and 4 Benefits

Hydroquinone Triluma: What Is It, Cost, How It Works and 4 Benefits

Hydroquinone Triluma

You examine your face in the mirror and notice that the small dark spot on your cheek has grown. Maybe you recently gave birth or just love hanging out at the beach. Maybe it’s melasma, or your inconsistent use of sunscreen has finally taken its toll on your skin and manifested into hyperpigmentation. Hyperpigmentation and melasma can significantly impact the appearance of your skin. But don’t lose hope! Thanks to modern science, you can restore your skin’s even tone!

One highly effective treatment often recommended by professionals for these skin conditions is Hydroquinone Triluma. 

Are you curious about this product? This article delves into everything you need to know about Hydroquinone Triluma treatment, including its cost, mechanism, benefits, usage and how it compares to other treatments.

What Is Hydroquinone Triluma?

Hydroquinone Triluma is an FDA-approved topical treatment formulated to address stubborn melasma and other forms of hyperpigmentation. It combines three active ingredients, each with a targeted function, making it an effective product for skin discolouration.

Key Ingredients and Primary Use

  1. Hydroquinone (4%). A skin-lightening agent that reduces melanin production. It helps reduce dark spots and pigmentation.
  2. Tretinoin (0.05%). A retinoid that accelerates skin cell turnover, promoting exfoliation and renewal of healthier skin layers.
  3. Fluocinolone Acetonide (0.01%). A mild corticosteroid that soothes inflammation, reduces redness and minimises irritation often associated with pigmentation treatments.

What is the Price of Hydroquinone/Triluma in Singapore?

The price of Hydroquinone Triluma in Singapore ranges from $128 to $250 per tube (15g). Prices may vary amongst clinics and pharmacies.

At Sozo Aesthetic Clinic, we use the original Triluma manufactured by Galderma. This is one of the widely used formulations and what we believe to be the most stable.

How Does Hydroquinone Triluma Work?

The efficacy of Hydroquinone Triluma lies in the synergistic action of its three active ingredients:

  1. Hydroquinone. This chemical targets melanin production by inhibiting tyrosinase, an enzyme crucial in pigment formation. This leads to a gradual lightening of dark spots and patches and helps prevent re-pigmentation.
  2. Tretinoin. It encourages exfoliation by increasing the turnover of skin cells. It improves epidermal penetration of hydroquinone and enhances pigment removal.
  3. Fluocinolone Acetonide. Alleviates inflammation and redness that might occur during treatment, ensuring better tolerance of the product.

Together, these ingredients deliver results in a shorter timeframe than using these components individually.

Benefits of Using Hydroquinone Triluma

Benefits of Using Hydroquinone Triluma

Using Hydroquinone Triluma offers several advantages, making it a good option for addressing pigmentation issues:

  • Tested to be effective for stubborn melasma. This product is specifically designed to treat moderate to severe melasma.
  • Combination treatment. It integrates three active ingredients, reducing the need for multiple separate products.
  • Faster results. It provides visible improvement when used consistently.
  • Targeted action. Addresses the underlying causes of pigmentation, including inflammation and melanin synthesis.

How to Use Hydroquinone Triluma Safely

Application Guidelines

To achieve the best results and minimise side effects, follow these usage instructions:

  • This medication is best used at night when you are not exposed to ultraviolet light.
  • Gently wash the treated areas with a mild cleanser before application.
  • Wash hands thoroughly before and after application.
  • Apply a thin layer to the affected areas once daily, preferably at night.
  • Avoid using excessive amounts to prevent skin irritation.

Precautions

  • Avoid sensitive areas. Do not apply near the eyes, mouth or broken skin.
  • Consistently use sunscreen. Protect your skin with a broad-spectrum sunscreen product (SPF 30 or higher) during the day to prevent further pigmentation. Re-apply sunscreen throughout the day.
  • Apply moisturiser in the morning and at night. Avoid skin dryness by using a moisturiser formulated for your skin type.
  • Wear protective clothing. Use hats or clothing to shield your skin from sun exposure.
  • Limit duration. Avoid prolonged use beyond the recommended period without consulting your doctor.

Side Effects of Hydroquinone Triluma

While Hydroquinone Triluma is an FDA-approved melasma treatment that is generally well-tolerated, it may cause some side effects:

Mild Side Effects

  • Redness
  • Skin dryness
  • Peeling
  • Temporary skin irritation or sensitivity

Rare but Serious Side Effects

If you experience severe reactions to this hydroquinone cream, discontinue use immediately and consult your aesthetic practitioner.

Who Should Avoid Hydroquinone Triluma?

A woman holding a mirror

This treatment is not suitable for everyone. Avoid using Hydroquinone Triluma if:

  • You are pregnant or breastfeeding
  • Have known allergies to any of the active ingredients
  • Have sensitive or broken skin

How Does Hydroquinone Triluma Compare to Other Treatments?

Alternatives to Triluma

  • Kojic Acid. A natural skin-lightening agent derived from fungi. While effective, it is milder than Hydroquinone.
  • Vitamin C. This antioxidant brightens the skin but may not work as quickly as Triluma.
TreatmentBenefitsLimitations
Hydroquinone TrilumaFast results, comprehensive actionRequires medical supervision
Kojic AcidNatural, suitable for sensitive skinSlower results
Vitamin CBrightens skin, antioxidant benefitsLimited efficacy for severe melasma

How Long Does Hydroquinone Triluma Take to Work?

Results from Hydroquinone Triluma can typically be seen within 4-8 weeks of consistent use. However, individual timelines may vary based on factors such as:

  1. Severity of pigmentation. More severe cases may take longer to show improvement.
  2. Skin type. Individuals with sensitive or reactive skin may experience a slower response.
  3. Adherence to instructions. Consistent application and proper use can impact the effectiveness of treatment.

When to Consult a Professional

It is essential to seek professional advice in the following situations:

  • Persistent side effects. If you experience redness, irritation or other symptoms that do not subside after 8 weeks.
  • No improvement. If there is no noticeable change after 8 weeks of consistent use.
  • Unusual skin colouration. If darkened skin or tiny red lines appear unexpectedly.
  • Severe burning sensation. Discontinue use and consult a doctor immediately.

Conclusion

Hydroquinone Triluma is an effective treatment for facial melasma and hyperpigmentation. Combining three potent ingredients, it offers a comprehensive solution to stubborn skin discolouration. However, proper usage, consistent application and dermatologist guidance are crucial to ensure safety and optimal results. 

Always be mindful of potential side effects, protect your skin with sunscreen, and avoid prolonged exposure to ultraviolet light. Do you have concerns or questions about this medication? Book a consultation with Sozo Aesthetic Clinic today!

Author

Medical Director

After graduating from the National University of Singapore, Dr Boey’s journey in aesthetics brought him to esteemed institutions such as Harvard Medical School, American Academy of Aesthetic Medicine and Queen Mary University of London in diverse cities like Seoul, London, Boston and New York.